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Given the increased prevalence of asthma, previous research suggesting that aspirin can reduce risk for asthma is of interest; however, a randomized study in women has been lacking. The Women’s Health Study (WHS) is a randomized, double-blind, controlled study of low-dose aspirin (100 mg every other day) versus vitamin E in the primary prevention of cancer and coronary artery disease (Journal Watch Women’s Health Oct 4 2005). In a secondary analysis of 37,000 participants, WHS researchers evaluated whether aspirin affected risk for adult-onset asthma in women without a history of the disorder.
During a mean follow-up of 9.7 years, 872 and 963 new diagnoses of asthma occurred in the aspirin and placebo groups, respectively (hazard ratio, 0.90…