Sex Differences in AMI Outcomes

Among patients with STEMI, early death rates were higher in women than in men.

Study results have suggested that many differences in outcomes for men and women with acute myocardial infarction (AMI) are related to disparities in quality of care. Based on data from the American Heart Association’s “Get with the Guidelines — Coronary Artery Disease” program (>75,000 patients admitted with AMI to 420 U.S. hospitals from 2001 to 2006), investigators assessed whether sex differences still exist in medical care and outcomes for AMI.

As expected, among enrolled patients, women were older (mean age, 73 vs. 65), had more comorbid conditions, more often presented with ST-segment-elevation MI (STEMI), and had higher in-hospital death rates than men (unadjusted rates, 8.2% vs. 5.7%; P<0.0001). In adjusted analysis, overall sex dif…

Reviewing Author

JoAnne M. Foody, MD

Disclosures

Consultant / Advisory boardAegerion; Amarin; Bristol-Myers Squibb; Janssen; Merck; Pfizer; Sanofi-Aventis; Boehringer Ingelheim

Leadership positions in professional societiesAmerican College of Cardiology, Cardiosmart (Co-chair)

JoAnne M. Foody, MD

Disclosures

Consultant / Advisory boardAegerion; Amarin; Bristol-Myers Squibb; Janssen; Merck; Pfizer; Sanofi-Aventis; Boehringer Ingelheim

Leadership positions in professional societiesAmerican College of Cardiology, Cardiosmart (Co-chair)