Twins Born Following ART Have Higher Risk for Morbidity Than Spontaneously Conceived Twins

ART twins had higher risk for adverse perinatal outcomes as well as hospital admissions during the first 3 years of life.

Twins have higher perinatal morbidity rates than singleton infants — but are twins who are conceived following assisted reproductive technology (ART) at greater risk than those conceived spontaneously? To resolve conflicting data, researchers in Western Australia conducted a cohort study using information collected about twins during a 7-year period. To remove bias, the investigators compared outcomes in all spontaneously conceived (SC) twins as well as the subset of unlike-sex (ULS) SC twins (i.e., dizygotic twins) with those in ART twins, who are predominantly dizygotic.

Analysis that was adjusted for potential confounders (e.g., socioeconomic status) showed that, compared with ULS SC twins, ART twins had higher risks for preterm birth, lo…

Reviewing Author

Robert W. Rebar, MD

Disclosures

Consultant/Advisory BoardMyovant Sciences, Inc.

Editorial BoardsEndoText; Clinical OB/GYN Alert

Leadership Positions in Professional SocietiesAmerican Society for Reproductive Medicine (Member, Ethics Committee)

Robert W. Rebar, MD

Disclosures

Consultant/Advisory BoardMyovant Sciences, Inc.

Editorial BoardsEndoText; Clinical OB/GYN Alert

Leadership Positions in Professional SocietiesAmerican Society for Reproductive Medicine (Member, Ethics Committee)

Twins Born Following ART Have Higher Risk for Morbidity Than Spontaneously Conceived Twins

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Reviewing Author