Metabolic Syndrome in Male Relatives of Women with Polycystic Ovary Syndrome

Obesity accounts for high prevalence of metabolic syndrome in fathers and brothers of women with polycystic ovary syndrome.

Polycystic ovary syndrome (PCOS) is a common endocrinopathy in women. Affected women have twice the risk for metabolic syndrome as women of similar age in the general population, but risk for metabolic syndrome in male relatives of women with PCOS is unknown. Researchers assessed the prevalence of metabolic syndrome among 211 fathers (mean age, 57) of PCOS women compared with that in 1153 men (age, ≥40) from the Third National Health and Nutrition Survey (NHANES III), and in 58 brothers (mean age, 29) of women with PCOS compared with that in 582 men (age range, 18–40) from NHANES III.

Compared with NHANES III men, substantially more fathers and brothers of women with PCOS were obese; also, more fathers (42% vs. 32%) and brothers (22% vs. 9%)…

Reviewing Author

Robert W. Rebar, MD

Disclosures

Consultant/Advisory BoardMyovant Sciences, Inc.

Editorial BoardsEndoText; Clinical OB/GYN Alert

Leadership Positions in Professional SocietiesAmerican Society for Reproductive Medicine (Member, Ethics Committee)

Robert W. Rebar, MD

Disclosures

Consultant/Advisory BoardMyovant Sciences, Inc.

Editorial BoardsEndoText; Clinical OB/GYN Alert

Leadership Positions in Professional SocietiesAmerican Society for Reproductive Medicine (Member, Ethics Committee)

Metabolic Syndrome in Male Relatives of Women with Polycystic Ovary Syndrome

Topics

Reviewing Author