Does Polycystic Ovary Syndrome Raise Risk for Cardiovascular Disease?

PCOS was associated with excess risk for incident diabetes and dyslipidemia during nearly 2 decades of follow-up.

Polycystic ovary syndrome (PCOS) is associated with an adverse cardiovascular risk profile, but is long-term prevalence of such risk factors actually higher? To address this question, investigators evaluated data from a cohort of 1127 women (age range at enrollment, 20–32) who were followed for 20 years in a study on coronary artery risk development. PCOS (identified based on self-report of clinical symptoms and measurement of serum androgens) was present in 53 women (4.7%) at baseline.

White race, nulliparity, and higher mean fasting insulin levels were more common among women with PCOS at baseline than among those without PCOS. Baseline prevalences of hypertension, diabetes, and dyslipidemia were similar in both groups; however, adjusted a…

Reviewing Author

Robert W. Rebar, MD

Disclosures

Consultant/Advisory BoardMyovant Sciences, Inc.

Editorial BoardsEndoText; Clinical OB/GYN Alert

Leadership Positions in Professional SocietiesAmerican Society for Reproductive Medicine (Member, Ethics Committee)

Robert W. Rebar, MD

Disclosures

Consultant/Advisory BoardMyovant Sciences, Inc.

Editorial BoardsEndoText; Clinical OB/GYN Alert

Leadership Positions in Professional SocietiesAmerican Society for Reproductive Medicine (Member, Ethics Committee)

Does Polycystic Ovary Syndrome Raise Risk for Cardiovascular Disease?

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Reviewing Author