LNG-IUS Use in Women with Inherited Bleeding Disorders

Heavy menstrual bleeding is common in women with inherited bleeding disorders (e.g., von Willebrand disease, platelet disorders, other clotting factor deficiencies; JW Womens Health Jul 9 2009). Such bleeding in these women can result in anemia and negative effects on quality of life. A major noncontraceptive benefit of the levonorgestrel-releasing intrauterine system (LNG-IUS) is its favorable effect on uterine bleeding; however, few studies have addressed use of this device in women with inherited bleeding disorders. Now, British investigators have conducted a case series in 26 women who used the LNG-IUS for >12 months. Participants completed pictorial blood-loss assessment charts (PBACs) and quality-of-life (QOL) questionnaires before LN…