International study reveals human papillomavirus incidence and rates of clearance.
Understanding the natural history of human papillomavirus (HPV) infection in men is important, not only for optimizing treatment and prevention, but also for minimizing risk for transmission to women. To determine HPV incidence and clearance rates in men, investigators followed 1159 men (age range, 18–70) in the U.S., Brazil, and Mexico for a median of 28 months. At study entry and every 6 months, swab samples from the genital area were collected and tested for 37 HPV genotypes.
Incidence of HPV infection was 38.4 per 1000 person-months. Overall, median time to clearance was 7.5 months, generally was similar for oncogenic and nononcogenic HPV types, and was faster in men who were 30 or older. However, median time to clearance for HPV-16 was …
Reviewing Author
DisclosuresConsultant/Advisory BoardAicuris; Bayer; GSK; Innovative Molecules; Merck; MAPP Biopharmaceutical (Safety Monitoring Committee)
RoyaltiesUpToDate
Grant/Research SupportNIH/National Institute of Allergy and Infectious Diseases; GSK; Moderna; Assembly Biomedical; Aicuris
Editorial BoardsSexually Transmitted Diseases; Sexually Transmitted Infections; Journal of Infectious Diseases
Leadership PositionsID Division Chiefs Community of Practice (At-Large Member)
DisclosuresConsultant/Advisory BoardAicuris; Bayer; GSK; Innovative Molecules; Merck; MAPP Biopharmaceutical (Safety Monitoring Committee)
RoyaltiesUpToDate
Grant/Research SupportNIH/National Institute of Allergy and Infectious Diseases; GSK; Moderna; Assembly Biomedical; Aicuris
Editorial BoardsSexually Transmitted Diseases; Sexually Transmitted Infections; Journal of Infectious Diseases
Leadership PositionsID Division Chiefs Community of Practice (At-Large Member)