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An estimated one in five U.S. women undergoes surgical repair for pelvic organ prolapse, and one quarter of these women develop new-onset urinary incontinence following surgery. In a government-funded, randomized, single-blind trial, women without incontinence who were having surgery for vaginal prolapse repair also received either a prophylactic midurethral sling or a sham incision.
In 327 evaluable women, the rate of urinary incontinence 12 months after surgery was 27.3% in the sling group versus 43.0% in the sham group (P=0.002). The number needed to treat with a sling to prevent one case of urinary incontinence at 12 months, allowing for subsequent treatment for incontinence, was 6.3. Prophylactic sling placement was associated with high…