CIN Treatment and Preterm Birth: Revisiting the Association

British study indicates that quality-assured treatment for cervical intraepithelial neoplasia does not raise obstetric risk.

Treatment for cervical intraepithelial neoplasia (CIN) has been associated with excess risk for subsequent preterm birth (e.g., JW Womens Health May 10 2007). In England, women with abnormal cervical cancer screening results are referred to clinics specializing in CIN evaluation (with colposcopy and, if needed, punch biopsy) and treatment (most commonly with loop excision procedures); all clinics and colposcopists are audited every 3 years. Investigators conducted a cohort study of >18,000 singleton births in women who underwent colposcopy followed by cervical punch biopsy (untreated group) or treatment for CIN (treated group) from 1987 through 2009 at 12 high-volume clinics. Women were followed retrospectively (prior births) and prospectiv…

Reviewing Author

Andrew M. Kaunitz, MD

Disclosures

RoyaltiesUpToDate

Grant/Research SupportMerck, Mithra, Medicines360

Editorial BoardsContraception; Menopause; Contraceptive Technology Update; OBG Management; Medscape OB/GYN & Women’s Health

Andrew M. Kaunitz, MD

Disclosures

RoyaltiesUpToDate

Grant/Research SupportMerck, Mithra, Medicines360

Editorial BoardsContraception; Menopause; Contraceptive Technology Update; OBG Management; Medscape OB/GYN & Women’s Health

CIN Treatment and Preterm Birth: Revisiting the Association

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Reviewing Author