Pulmonary and Venous Thromboembolism After In Vitro Fertilization

Absolute risk was modestly higher than that associated with spontaneous pregnancy and was highest during the first trimester.

Pregnancy raises risk for venous thromboembolism (VTE) — but does in vitro fertilization (IVF), given the high endogenous estrogen levels achieved during ovarian stimulation, increase this risk still further during the ensuing pregnancy? Swedish investigators analyzed data from national registers between 1990 and 2008 to assess risk for VTE and pulmonary embolism (PE) in 23,498 women with first pregnancies following IVF compared with 116,960 women with spontaneous first pregnancies matched for maternal age and year of delivery (median age of all women, 33).

Incidence of VTE was 4.2/1000 in pregnant women who underwent IVF and 2.5/1000 in those who conceived spontaneously. Risk for VTE after IVF was higher during the entire pregnancy (hazard …

Reviewing Author

Robert W. Rebar, MD

Disclosures

Consultant/Advisory BoardMyovant Sciences, Inc.

Editorial BoardsEndoText; Clinical OB/GYN Alert

Leadership Positions in Professional SocietiesAmerican Society for Reproductive Medicine (Member, Ethics Committee)

Robert W. Rebar, MD

Disclosures

Consultant/Advisory BoardMyovant Sciences, Inc.

Editorial BoardsEndoText; Clinical OB/GYN Alert

Leadership Positions in Professional SocietiesAmerican Society for Reproductive Medicine (Member, Ethics Committee)

Pulmonary and Venous Thromboembolism After In Vitro Fertilization

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Reviewing Author