High coverage with quadrivalent HPV vaccine has dramatically reduced the incidence of genital warts in Australia.
In clinical trials, the quadrivalent human papillomavirus (HPV) vaccine provides excellent protection against genital warts. Now, Australian investigators have shown high effectiveness of the vaccine in a nationwide program begun in 2007 that has led to routine, free vaccination of women aged 12 to 26.
From 2007 through 2011, rates of new genital-wart diagnoses fell from 11.5% to 0.85% in women younger than 21 and from 11.3% to 3.1% in women aged 21 to 30. Moreover, HPV infection declined by 82% among heterosexual men younger than 21 and by 51% in men aged 21 to 30. Modest declines in men who have sex with men were also noted. No changes in chlamydia incidence were observed.
Reviewing Author
DisclosuresConsultant/Advisory BoardAicuris; Bayer; GSK; Innovative Molecules; Merck; MAPP Biopharmaceutical (Safety Monitoring Committee)
RoyaltiesUpToDate
Grant/Research SupportNIH/National Institute of Allergy and Infectious Diseases; GSK; Moderna; Assembly Biomedical; Aicuris
Editorial BoardsSexually Transmitted Diseases; Sexually Transmitted Infections; Journal of Infectious Diseases
Leadership PositionsID Division Chiefs Community of Practice (At-Large Member)
DisclosuresConsultant/Advisory BoardAicuris; Bayer; GSK; Innovative Molecules; Merck; MAPP Biopharmaceutical (Safety Monitoring Committee)
RoyaltiesUpToDate
Grant/Research SupportNIH/National Institute of Allergy and Infectious Diseases; GSK; Moderna; Assembly Biomedical; Aicuris
Editorial BoardsSexually Transmitted Diseases; Sexually Transmitted Infections; Journal of Infectious Diseases
Leadership PositionsID Division Chiefs Community of Practice (At-Large Member)