Transmission of MDR-TB in the U.S.

In the U.S., 22% of multidrug-resistant tuberculosis cases resulted from transmission within the country, and 22% stemmed from imported active disease.

Multidrug-resistant (MDR) tuberculosis (TB) accounts for about 1% of newly diagnosed TB cases in the U.S., but what proportion of MDR-TB cases is attributable to transmission within the country? To find out, investigators carried out a cross-sectional study involving verified cases of MDR-TB from eight states (California, Texas, Colorado, Maryland, Massachusetts, New York, Tennessee, and Washington) between 2007 and 2009.

Among 268 cases of MDR-TB in the U.S. during the study period, 168 were reported from these eight states. In-depth interviews were completed with the 92 individuals who consented. Cases were categorized based on genotyping and epidemiological links.

Among the 92 cases with information available, 22% resulted from transmissio…

Reviewing Author

Mary E. Wilson, MD

Disclosures

Consultant/Advisory BoardOneHealthTrust (formerly Center for Disease Dynamics, Economics, and Policy); Global Health Institute, University of Wisconsin

RoyaltiesUpToDate

Editorial BoardsJournal of Travel Medicine

Mary E. Wilson, MD

Disclosures

Consultant/Advisory BoardOneHealthTrust (formerly Center for Disease Dynamics, Economics, and Policy); Global Health Institute, University of Wisconsin

RoyaltiesUpToDate

Editorial BoardsJournal of Travel Medicine

Transmission of MDR-TB in the U.S.

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Reviewing Author