Cerebrovascular Disease Among HIV-Infected Adults in the Southeastern U.S.

More evidence suggesting that HIV infection, despite antiretroviral therapy, confers excess risk for age-related diseases

Although the incidences of central nervous system–related opportunistic infections and AIDS dementia have declined dramatically since the advent of antiretroviral therapy (ART), the proportion of HIV-infected patients who have experienced cerebrovascular events (CVEs) has remained high. In a recent study, researchers assessed the incidence and possible causes of CVEs (i.e., ischemic strokes, hemorrhagic strokes, or transient ischemic attacks) among more than 2500 HIV-infected adults (median age at study entry, 39; median CD4 count, 351 cells/mm³; 27% with HIV RNA <400 copies/mL; 46% on ART) who were receiving care in a large public hospital in North Carolina between 1999 and 2010.

During a median follow-up of 4.5 years, 53 CVEs occurred (med…

Reviewing Author

Nina H. Lin, MD

Cerebrovascular Disease Among HIV-Infected Adults in the Southeastern U.S.

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Reviewing Author