Potentially Modifiable Risk Factors in Adolescence for Young-Onset Dementia

An analysis of men conscripted into the Swedish military suggests many factors are modifiable, but genetics remain important as well.

Young-onset dementia (YOD) is dementia diagnosed before age 65. It is often related to causative genes, but much research has been done to identify other risk factors. In one study, the prevalence of dementia was 54 per 100,000 with onset between ages 30 and 65and 98 per 100,000 between 45 and 65 (J Neurol Neurosurg Psychiatr 2003; 74:1206). In that study, the epidemiology of YOD was classified as follows: Alzheimer disease 34%, vascular dementia 18%, frontotemporal lobe degeneration 12%, dementia with Lewy bodies 7%, alcoholic dementia 10%, and other 19%. Other studies have had similar findings.

In this cohort study, researchers examined risk factors for YOD among 488,484 men conscripted at a mean age of 18 into the Swedish military service…

Reviewing Author

Jaime Toro, MD

Disclosures

Editorial BoardsMultiple Sclerosis and Related Disorders

Jaime Toro, MD

Disclosures

Editorial BoardsMultiple Sclerosis and Related Disorders

Potentially Modifiable Risk Factors in Adolescence for Young-Onset Dementia

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Reviewing Author