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To assess the prognostic value of high-sensitivity cardiac troponin-T (hs-cTnT) for in-hospital mortality in patients with infection, researchers in the Netherlands enrolled 404 consecutive emergency department (ED) patients with suspected infection over a 1-year period; 292 of these patients had hs-cTnT measured. Very low-risk ED patients and patients in whom no infection was identified were excluded.
The overall mortality rate was 6%. Nonsurvivors were older (67 vs. 56 years) and had higher cancer rates (48% vs. 12%) than survivors. Nonsurvivors had higher median values for hs-cTnT (57 vs. 15 ng/L), lactate (2.8 vs. 1.8 mmol/L), urea (11 vs. 6 mmol/L), and creatinine (104 vs. 81 µg/L). Hs-cTnT was an independent predictor of in-hospital mo…