Cirrhosis Increases Mortality Risk in Peptic Ulcer Bleeding

In a large sample of U.S. patients hospitalized for peptic ulcer bleeding, having cirrhosis was associated with a 3.3-fold higher risk for dying.

Cirrhosis has been associated with worse outcomes in patients with peptic ulcer bleeding (PUB; Hepatology 2012; 56:698). To evaluate this possible association further, investigators compared in-hospital mortality, length of hospital stay, and hospitalization costs between patients with and without cirrhosis who were hospitalized for PUB.

Using the U.S. National Inpatient Sample for 2009, investigators analyzed data on 96,877 patients discharged with PUB, of whom 3574 had cirrhosis and 93,313 did not. Cirrhosis was further classified as compensated (no variceal bleeding, ascites, or hepatorenal syndrome) or decompensated.

Patients with cirrhosis were younger, had a higher comorbidity score, and had higher rates of malnutrition and coagulopathy…

Reviewing Author

David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)

Disclosures

Nothing to disclose

David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)

Disclosures

Nothing to disclose

Cirrhosis Increases Mortality Risk in Peptic Ulcer Bleeding

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Reviewing Author