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Sleeve gastrectomy is a restrictive bariatric procedure in which a large portion of the stomach's greater curvature is resected. In this randomized trial, Swiss surgeons compared sleeve gastrectomy with Roux-en-Y gastric bypass in 217 patients (mean age, 43; mean body-mass index, 43 kg/m2; mean weight, 124 kg).
The 30-day complication rate was somewhat lower with sleeve gastrectomy than with bypass (8% vs. 17%; P=0.07); infections accounted for most of the difference. One patient (in the bypass group) died postoperatively. At 1 year, mean weight loss was similar in the two groups (37 kg with sleeve gastrectomy; 40 kg with bypass).
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This trial is by far the largest randomized comparison of sleeve g…