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Definitive criteria are lacking for initiation of extracorporeal membrane oxygenation (ECMO) in patients with acute respiratory distress syndrome (ARDS). To identify predictors of mortality in such patients, researchers at a referral center in France prospectively analyzed data from 85 consecutive ARDS patients retrieved from referring hospitals for ECMO treatment during a 3.5-year period. Patients aged >70 with chronic heart, lung, or kidney disease, or with sequential organ failure assessment (SOFA) scores >18 were excluded.
Patients had severe hypoxia and respiratory acidosis (PaCO2 >70 mm Hg; pH <7.2). ARDS etiologies included community-acquired bacterial pneumonia (35%), influenza pneumonia (23%), and nosocomial pneumonia (14%). More th…