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Use of minimally invasive techniques (endoscopic, surgical, or percutaneous) is sometimes necessary to remove suspected infected pancreatic necrosis. In this setting, the role of routine fine-needle aspiration (FNA) — either for accurate diagnosis or for identifying the responsible organism to tailor antibiotic therapy — is debated, and practice guidelines provide varying recommendations (Pancreatology 2013; 13:e1 and Am J Gastroenterol 2013; 108:1400).
In the current post-hoc analysis of data from a multicenter, prospective registry study in the Netherlands, investigators evaluated the role of FNA in diagnosing infected pancreatic necrosis in 208 patients who underwent some intervention (surgical, endoscopic, or percutaneous) to treat that …