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The study of HIV transmission networks is usually limited geographically by investigators based within a single country or region. A detailed understanding of the global spread of HIV could improve strategies for HIV prevention and control. To tackle this challenge, researchers studied HIV sequences in the Los Alamos National Laboratory HIV sequence database from more than 84,000 individuals representing 141 countries/regions.
Using sequence similarity as a marker of potential transmission linkage, the authors were able to classify more than 13,000 patients as being part of HIV transmission networks. They also were able to identify new transmission clusters and extend previously described transmission networks across international borders. T…