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Hypertension in midlife is associated with increased risk for dementia. To examine the effects of duration and treatment of hypertension on cognitive decline, investigators in the Netherlands examined data from a prospective, 12-year study involving 1805 cognitively intact adults aged 25 to 84. Participants were classified as having no hypertension (64.6%), controlled hypertension (4.9%), untreated hypertension (7.9%), or poorly controlled hypertension (22.6%).
The rate of prevalent hypertension at baseline was 35.3%, and the rate of incident hypertension at 6- or 12-year follow-up was 30.2%. Memory, executive functioning, and information-processing speed all declined faster in participants who had hypertension at baseline than in those who …