Pregnancy Illuminates Heterogeneity of PCOS

Only those women with polycystic ovary syndrome plus hyperandrogenemia had excess risk for certain obstetric complications.

Polycystic ovary syndrome (PCOS) is a heterogeneous disorder characterized by at least two of the following features: irregular menses, polycystic ovaries, and hyperandrogenism. Women with PCOS are at excess risk for various pregnancy complications. To examine this issue more closely, investigators compared singleton pregnancy outcomes in 459 women with PCOS who attended a private Danish infertility clinic with outcomes in a general population of 5409 women delivering at a large Danish hospital.

After adjustment for factors such as body-mass index (BMI), parity, and maternal age, women with PCOS had increased risk for preterm delivery before 37 weeks' gestation (odds ratio, 2.3; P<0.0001) and marginally increased risk for preeclampsia (OR, 1…

Reviewing Author

Robert W. Rebar, MD

Disclosures

Consultant/Advisory BoardMyovant Sciences, Inc.

Editorial BoardsEndoText; Clinical OB/GYN Alert

Leadership Positions in Professional SocietiesAmerican Society for Reproductive Medicine (Member, Ethics Committee)

Robert W. Rebar, MD

Disclosures

Consultant/Advisory BoardMyovant Sciences, Inc.

Editorial BoardsEndoText; Clinical OB/GYN Alert

Leadership Positions in Professional SocietiesAmerican Society for Reproductive Medicine (Member, Ethics Committee)

Pregnancy Illuminates Heterogeneity of PCOS

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Reviewing Author