Margins for Conservative Surgery in Stage I and II Invasive Breast Cancer

These evidence-based guidelines for breast-conserving surgery with whole-breast irradiation are essential for reducing unnecessary repeat lumpectomy or mastectomy.

Approving/Endorsing Organizations: Society of Surgical Oncology, American Society for Radiation Oncology, American Society of Breast Surgeons

Target Population: Surgeons, radiation oncologists, medical oncologists, pathologists

Background and Objective

One of the most controversial issues in breast cancer management concerns the margin width required for invasive breast cancer treated with lumpectomy and whole-breast radiotherapy. Additional surgery for close margins may be unnecessary, may adversely affect cosmetic outcomes, and may add unnecessary costs to healthcare. These consensus guidelines are based on a meta-analysis of margin width and tumor recurrence in 28,162 patients who underwent breast-conserving surgery and whole-breast radioth…

Reviewing Author

Henry Mark Kuerer, MD, PhD, FACS

Disclosures

Speaker's BureauPhysicians’ Education Resource, LLC

RoyaltiesMcGraw-Hill Professional; UpToDate, Inc.

Editorial BoardsAnnals of Surgical Oncology

Leadership Positions in Professional SocietiesAmerican Society of Breast Surgeons (Chair, Publications Committee)