Use of Antiretroviral Drugs in Pregnancy

Specific drug information is updated, but the recommendations for treating neonates remain unchanged.

Sponsoring Organization: U.S. Department of Health and Human Services

Target Population: Primary care providers, obstetricians, pediatricians

Background and Objective

Increasing experience with older antiretrovirals (ARVs) and the availability of several new ones prompted a re-examination of these guidelines, which were last updated in July 2012. Recent reports of several HIV-infected neonates with good responses to nonstandard regimens were also considered.

Key Points and Recommendations

All HIV-infected women who are contemplating pregnancy should be on a maximally suppressive ARV regimen.
Neither tenofovir nor abacavir has to date been associated with excess risk for birth defects. Hence, these drugs and the combination pills containing them j…

Reviewing Author

Abigail Zuger, MD

Disclosures

Nothing to disclose