Updated DHHS HIV Treatment Guidelines

This major revision includes a recommendation for less-frequent CD4-count monitoring, an updated list of recommended regimens, a discussion of “switching,“ and a new section on treatment costs.

Sponsoring Organization: U.S. Department of Health and Human Services

Target Population: Healthcare providers involved in the treatment of HIV infection

Background and Objective

This document updates guidelines last revised in February 2013.

What's Changed

The recommended frequency of CD4-count monitoring has been decreased for patients on antiretroviral therapy (ART) for >2 years with consistent viral suppression.
The classification of initial combination ART regimens has been changed from “preferred” to “recommended,” and the number of recommended regimens has been increased. Some older drugs are no longer recommended for initial therapy.
“Regimen Simplification” has been updated to “Regimen Switching in the Setting of Viral Suppression,” with g…

Reviewing Author

Charles B. Hicks, MD

Disclosures

Consultant / Advisory boardGilead Sciences; ViiV; Merck

RoyaltiesUpToDate, Inc.

Grant / Research supportNIH; Department of Health and Human Services