Dietary Approaches to Treating EoE: A Meta-Analysis

Results were best with the elemental diet but strong and more generalizable with the less onerous six-food elimination diet.

Eosinophilic esophagitis (EoE) has been categorized as a food allergy because of evidence of disease remission with dietary elimination, which should be considered as an initial therapy in both children and adults with EoE (NEJM JW Gastroenterol Jun 7 2013). In choosing the optimal dietary intervention (elemental, empiric elimination, or targeted elimination) for patients, clinicians are currently hampered by variable findings on their effectiveness.

In a systematic review and meta-analysis, researchers evaluated the efficacy of dietary interventions to induce histologic remission in EoE (peak eosinophil counts <15 eosinophils per high-power field).

Results based on data from 23 articles and 10 abstracts were as follows:

The overall efficacy f…

Reviewing Author

David A. Johnson, MD

Disclosures

Consultant/Advisory boardMedscape/WebMD; Pfizer; CRH Medical Corporation; Aries

EquityCRH Medical Corporation

Editorial boardsMedscape Gastroenterology

Leadership positions in professional societiesAmerican College of Gastroenterology Research Institute Board of Directors