Loading...
Evidence suggests an inverse relation exists between serum 25-hydroxyvitamin D (25[OH]D) level and mortality. In this meta-analysis of individual participant data from eight prospective European and U.S. studies, investigators determined whether 25(OH)D levels were associated with cardiovascular (CV)-related, cancer-related, and all-cause mortality in 26,000 older adults (age range, 50–79).
During median follow-up ranging from 4 to 16 years, 6700 deaths occurred. All-cause mortality was 1.6-fold higher among participants in the lowest quintile of serum vitamin D levels than among those in the highest quintile. Results were similar for CV-related mortality in patients with and without known CV disease (risk ratios, 1.7 and 1.4, respectively) …