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When surgical bioprostheses develop structural deterioration, as evidenced by stenosis or regurgitation, repeat cardiac surgery carries increased risk. Transcatheter aortic valve replacement (TAVR) is a feasible alternative for some high-risk patients, but there is little data on long-term outcomes and in large numbers of patients. In this report from the Valve-in-Valve International Data (VIVID) Registry, investigators pooled data from 55 centers on 459 patients (mean age, 78) who developed bioprosthetic stenosis (39%), regurgitation (30%), or both (30%), and were treated with balloon-expandable (54%) or self-expanding (46%) TAVR devices. The median Society of Thoracic Surgeons (STS) predicted risk for mortality at 30 days was 10%.
Mortalit…