Who Needs Screening Colonoscopy?

Multiple models have used predictive factors to identify patients at differing risks for colorectal cancer (CRC) with the aim of targeting colonoscopy to higher-risk groups and safer, less-costly modalities to lower-risk groups. Unfortunately, these models fail to achieve sufficient discrimination to be useful in clinical practice.

In the current study, investigators created a score to predict the risk for advanced neoplasia at screening colonoscopy. The study group comprised 35,918 participants (age range, 40 to 66 years; race, white) with advanced neoplasia (cancer or advanced adenomas) from a nationwide screening program in Poland. Traditional serrated adenomas, sessile serrated polyps or adenomas, and mixed serrated polyps were considere…