Antithrombotic Therapy Prevents Recurrent Stroke in Children with Bacterial Meningitis

Heparin was more effective than aspirin.

Bacterial meningitis, although declining in incidence, continues to cause serious morbidity, including ischemic stroke. In a retrospective review of the Canadian Pediatric Ischemic Stroke Registry, researchers assessed the efficacy of antithrombotic therapy in preventing recurrent ischemic stroke in children with bacterial meningitis.

The study cohort comprised 22 children (median age, 13 months; age range, 35 days–17.5 years; 64% boys) with bacterial meningitis who developed ischemic stroke (at a median of 3 days after first symptoms of infection). All patients had undergone ≥2 neuroimaging studies at one of two children's hospitals. Bacterial agents included Streptococcus pneumoniae (10 patients), S. agalactiae (4), Mycobacterium tuberculo…

Reviewing Author

F. Bruder Stapleton, MD

Disclosures

Consultant/Advisory BoardCareer Physician

Editorial BoardsUpToDate

Leadership Positions in Professional SocietiesAmerican Society of Pediatric Nephrology Foundation (Chair)

F. Bruder Stapleton, MD

Disclosures

Consultant/Advisory BoardCareer Physician

Editorial BoardsUpToDate

Leadership Positions in Professional SocietiesAmerican Society of Pediatric Nephrology Foundation (Chair)

Antithrombotic Therapy Prevents Recurrent Stroke in Children with Bacterial Meningitis

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Reviewing Author