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Recently, best-care practices in screening and intervention for Barrett esophagus (BE) have received considerable attention in the medical literature. Despite the fact that BE is precancerous, no proof yet exists that screening and surveillance prevent deaths from esophageal adenocarcinoma (EAC). In the current review, two recognized experts summarized the pathogenesis, diagnosis, epidemiology, and management of BE. Key points include the following:
The most-recent, highest-quality studies suggest that the incidence of EAC in patients with BE is 0.1% to 0.3% per year. Risk for EAC is higher in men (twice as high compared with women) and with longer segments of BE. Risk decreases if sequential endoscopies show no progression to dysplasia.
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