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There is no gold standard for the diagnosis of cellulitis. Failure to recognize it or to prescribe antibiotic therapy can be associated with morbidity and even mortality. However, it is clear that antibiotic therapy is overused, and it is possible that such overuse might produce resistant strains of bacteria. It is not infrequent in my practice, to be referred patients with “recalcitrant bilateral cellulitis” whose correct diagnosis is stasis dermatitis. Recognizing such patients before antibiotic use or hospitalization would likely be cost saving.
To test whether dermatology consults for patients with suspected cellulitis could reduce inappropriate treatment of mimicking conditions, these authors conducted a prospective, nonrandomized study at a major academic center. Among 29 patients diagnosed with cellulitis by primary care physicians, 20 were randomized to be seen by dermatology consultants before receiving antibiotic therapy (treatment group) and 9 were randomized to care only by their PCPs (control group). In the control group, one third received antibiotics and one patient was hospitalized. In the treatment group, only two patients (10%) had dermatologist-confirmed cellulitis. The rest received final diagnoses of eczematous dermatitis (n = 4); stasis dermatitis (3); erythema migrans (3); arthropod reaction (2); and one each phytophotodermatitis, gout, molluscum contagiosum, hematoma, erythema nodosum, and chronic paronychia.
Arakaki RY et al. The impact of dermatology consultation on diagnostic accuracy and antibiotic use among patients with suspected cellulitis seen at outpatient internal medicine offices: A randomized clinical trial. JAMA Dermatol 2014 Aug 20; [e-pub ahead of print]. (http://dx.doi.org/10.1001/jamadermatol.2014.1085)
Hughey LC.The impact dermatologists can have on misdiagnosis of cellulitis and overuse of antibiotics: Closing the gap. JAMA Dermatol 2014 Aug 20; [e-pub ahead of print]. (http://dx.doi.org/10.1001/jamadermatol.2014.1164)
Comment
Although this study considers only cellulitis, misdiagnosis and mistreatment of skin disease is widespread. Unfortunately, there is not enough time in medical school curricula to teach dermatology and rectify this educational gap. In addition, there are not enough dermatologists to see all the patients with skin disease. Until such time as more skin specialists are able to observe patients, we should do our best to educate primary care physicians, hospitalists, and emergency room physicians about common misdiagnoses and develop protocols by which dermatologists can easily see patients before hospitalization.