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Treatment options are limited for patients with back-related leg pain. Researchers in Minnesota and Iowa randomized 192 adults (mean age, 57) who had radiating pain from the lumbar spine into a lower extremity (duration, ≥4 weeks) to 12 weeks of either home exercise and advice alone, or exercise and advice plus spinal manipulative therapy. Spinal-manipulation patients received ≤20 sessions with chiropractors who delivered high-velocity, low-amplitude thrust procedures or low-velocity, variable-amplitude mobilization maneuvers to the lumbar vertebral or sacroiliac joints, plus adjunctive therapies (e.g., soft-tissue stretching) as needed. Patients in both groups received four 1-hour home exercise and advice visits, designed to help them mana…