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The Surgical Treatment of Ischemic Heart Failure (STICH) trial was a randomized, controlled trial that evaluated the incremental benefit of bypass surgery compared with guideline-based medical therapy in patients with severe systolic dysfunction due to coronary artery disease. STICH showed a nonsignificant difference between medical therapy alone and medical therapy plus coronary artery bypass grafting (CABG) for the primary outcome of death (NEJM JW Cardiol Apr 4 2011). A prespecified secondary endpoint was quality of life (QOL). For the 1212 patients enrolled in STICH, the researchers obtained QOL measurements at baseline and 4, 12, 24, and 36 months after randomization.
At baseline, QOL scores were similar between the treatment groups. Fo…