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Atypical antipsychotic medications increase risks for weight gain, insulin resistance, and diabetes. A randomized, controlled trial conducted in an intensive outpatient psychiatric rehabilitation program, and shorter-term studies have demonstrated the value of programs addressing eating, weight management, and exercise. In the current 12-month study, researchers randomized 200 overweight patients taking antipsychotics to a group intervention or usual care. Patients were recruited from an integrated healthcare system and two community mental health centers.
The intervention consisted of 6 months of weekly group meetings focusing on individualized dietary and behavioral self-management, moderate calorie restriction, and physical activity, foll…