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Prenatal genetic testing has become a daunting maze of options for patients and clinicians alike. Investigators in the San Francisco Bay Area conducted a randomized, controlled trial of a computerized decision-support tool plus availability of prenatal testing at no out-of-pocket cost. The primary outcome of this study involving 710 pregnant women was use of chorionic villus sampling or amniocentesis.
Compared with women who received usual care, those who used the hour-long prenatal testing tool were less likely to undergo invasive diagnostic testing (5.9% vs. 12.3%; P=0.005) and more apt to waive testing entirely (25.6% vs. 20.4%; P=0.005). Women in the intervention group also were more knowledgeable about age-related risks for aneuploidy a…