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Two research groups report encouraging results in treating and preventing Ebola infections in nonhuman primates.
An international team tested a combination of several monoclonal antibodies (ZMapp) that has shown efficacy against Ebola virus in primates (rhesus macaques). The antibodies were administered to 18 monkeys, with the first dose given 3 to 5 days after the animals were inoculated with the virus. Three control animals were inoculated with the virus but not treated. Almost all of the animals experienced symptoms and signs of Ebola infection and had laboratory markers of disease at the time of first antibody treatment. All of the treated animals survived, whereas all of the controls died.
A second international team reported progress wi…