Is Cardiovascular Function Altered in the Offspring of IVF-Treated Women?

Although studies have shown differences, clinical significance remains to be established.

Children born after in vitro fertilization (IVF) may have subtle alterations in cardiovascular function. Hypothesizing that the ovarian hyperstimulation associated with IVF might be causative, Chinese investigators assessed cardiovascular parameters with echocardiography in 41 children born to women who experienced ovarian hyperstimulation syndrome (OHSS) during IVF, 34 children of mothers with non-OHSS IVF, and 48 spontaneously conceived (SC) children (overall mean age, 4.5 years).

Children of OHSS mothers had echocardiographic findings suggestive of diminished left ventricular function; they also had smaller-diameter common carotid arteries with impaired flow-mediated dilation. Values in the non-OHSS IVF children fell between the OHSS and …

Reviewing Author

Robert W. Rebar, MD

Disclosures

Consultant/Advisory BoardMyovant Sciences, Inc.

Editorial BoardsEndoText; Clinical OB/GYN Alert

Leadership Positions in Professional SocietiesAmerican Society for Reproductive Medicine (Member, Ethics Committee)

Robert W. Rebar, MD

Disclosures

Consultant/Advisory BoardMyovant Sciences, Inc.

Editorial BoardsEndoText; Clinical OB/GYN Alert

Leadership Positions in Professional SocietiesAmerican Society for Reproductive Medicine (Member, Ethics Committee)

Is Cardiovascular Function Altered in the Offspring of IVF-Treated Women?

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Reviewing Author