Compared with a fairly aggressive baseline strategy, using coronary computed tomography angiography to calibrate preventive therapies doesn't seem to add much.
Despite advances in cardiovascular (CV) prevention, some patients, including those with diabetes, remain at risk for coronary events. Imaging modalities identify preclinical atherosclerotic burden, but whether the results can be used to improve preventive interventions in asymptomatic, high-risk patients remains unproven. To determine the usefulness of coronary computed tomography angiography (CCTA), researchers conducted a single-center, randomized, controlled trial, enrolling 900 patients with type I or type II diabetes (mean age, 62; 52% men; mean duration of diabetes, 13 years).
Treatment arms were standard, guideline-directed, preventive care (treatment targets: glycated hemoglobin [HbA1c], <7.0%; low-density lipoprotein [LDL], <100 mg/…
Reviewing Author
DisclosuresConsultant/Advisory BoardBristol Myers Squibb; CPC Clinical Research
Grant/Research SupportNational Heart, Lung, and Blood Institute
Editorial BoardsUpToDate; American College of Cardiology Self-Assessment Program (SAP)
Leadership Positions in Professional SocietiesAmerican College of Cardiology (Chair, Innovations Committee)
DisclosuresConsultant/Advisory BoardBristol Myers Squibb; CPC Clinical Research
Grant/Research SupportNational Heart, Lung, and Blood Institute
Editorial BoardsUpToDate; American College of Cardiology Self-Assessment Program (SAP)
Leadership Positions in Professional SocietiesAmerican College of Cardiology (Chair, Innovations Committee)