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In animal and human laboratory studies, nicotine produces pleasure and increases the reward value of nondrug stimuli. Deprivation of nicotine is associated with decreased reward experiences and with anhedonia. The current researchers examined whether anhedonia is a symptom of tobacco withdrawal that contributes to smoking-cessation outcomes.
The participants were 1175 smokers (≥10 cigarettes daily for the preceding 6 months; women, 58%; white, 85%; mean age, 45) who were motivated to quit and were enrolled in a smoking-cessation study, and who rated pleasure associated with daily activities, negative affect, craving, trouble with concentrating, and hunger. Ratings were completed for the 5 days before the quit date and the 10 days after.
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