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I am pleased to introduce this year's NEJM Journal Watch Neurology Top Ten Stories of 2014. As in years past, I have made these selections after carefully reviewing all of the past year's summaries. In making the choices, I have tried to strike a balance between relevance to the clinician, recognition of landmark studies, and media publicity and public awareness. The sequence of stories is not intended to reflect their relative importance. I hope you find the list useful and thought-provoking.
Our Neurology Top Stories of 2014 are:
The Frustration of ALS Therapy Development
No Evidence for Selective Use of Alteplase Based on Age or Stroke Severity
Finally, Migraine-Specific Preventive Therapy Is on the Horizon
Should We Consider Deep Brain Stimulation for Cervical Dystonia?
Head-to-Head Comparison of IV and Oral Methylprednisolone for MS Relapses
Epilepsy Case Definition Updated
Which Parenteral Treatment Is Best for Acute Migraine?
Vitamin E Outpaces Memantine in Mild-to-Moderate Alzheimer Disease
Intervention for Unruptured Brain AVMs Proves Very Harmful in the Short Term