Dengue Transmission Returns to Tokyo

Seventy years after the last local outbreak in Japan, the virus strikes again.

From late August through October 2014, 160 cases of autochthonous dengue fever were reported in Japan, where local transmission was last documented 70 years ago. The National Center for Global Health and Medicine confirmed 19 of the new cases (median patient age, 33). None of the 19 patients reported any overseas travel during the preceding 3 months. Fifteen had recently visited Tokyo's Yoyogi Park; the other 4 had visited other Tokyo parks.

Sixteen of the patients were hospitalized; 1 with a history of dengue fever (in 2006) met WHO criteria for dengue hemorrhagic fever. All patients recovered without sequelae. Eighteen of the 19 patients were confirmed as having as dengue virus serotype 1. Phylogenetic analysis of the envelope protein geno…

Reviewing Author

Mary E. Wilson, MD

Disclosures

Consultant/Advisory BoardOneHealthTrust (formerly Center for Disease Dynamics, Economics, and Policy); Global Health Institute, University of Wisconsin

RoyaltiesUpToDate

Editorial BoardsJournal of Travel Medicine

Mary E. Wilson, MD

Disclosures

Consultant/Advisory BoardOneHealthTrust (formerly Center for Disease Dynamics, Economics, and Policy); Global Health Institute, University of Wisconsin

RoyaltiesUpToDate

Editorial BoardsJournal of Travel Medicine

Dengue Transmission Returns to Tokyo

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Reviewing Author