Although ESRD rates are declining, they remain higher in HIV-infected patients (particularly blacks) than in the general population.
Although the incidence of HIV-associated nephropathy has declined since the advent of potent combination antiretroviral therapy (ART), HIV-infected individuals remain at risk for renal disease. To assess contributing factors and recent trends, investigators analyzed cases of end-stage renal disease (ESRD) in 11 NA-ACCORD clinical cohorts between 2000 and 2009.
A total of 286 incident cases of ESRD were identified among 38,354 HIV-infected adults. In adjusted analyses, risk factors for ESRD included black race, lower CD4-cell counts, lower baseline renal function, and comorbid conditions (diabetes mellitus, hypertension, hepatitis C); in addition, unsuppressed HIV RNA, which was more common among blacks, was a strong predictor of developing E…
Reviewing Author
DisclosuresGrant/Research SupportNIH
Editorial BoardsUpToDate; ID Images (idimages.org); Infectious Diseases Society of America COVID-19 Treatment Guidelines; International Antiviral Society–USA (Guidelines Committee)
Leadership Positions in Professional SocietiesHIV Medicine Association; Infectious Diseases Society of America (Board of Directors)
DisclosuresGrant/Research SupportNIH
Editorial BoardsUpToDate; ID Images (idimages.org); Infectious Diseases Society of America COVID-19 Treatment Guidelines; International Antiviral Society–USA (Guidelines Committee)
Leadership Positions in Professional SocietiesHIV Medicine Association; Infectious Diseases Society of America (Board of Directors)