Is Widespread Use of Intracytoplasmic Sperm Injection in IVF Warranted?

ICSI does not seem to improve reproductive outcomes, except among infertile males.

Since its introduction in 1992, intracytoplasmic sperm injection (ICSI) has enabled many couples with male factor infertility to bear children. However, this technique has also been used in many other couples undergoing in vitro fertilization (IVF) because it ensures that fertilization occurs. CDC investigators analyzed National Assisted Reproductive Technology Surveillance System data from 1996 to 2012 to assess national trends and reproductive outcomes of fresh IVF cycles using ICSI compared with conventional IVF.

Of nearly 1.4 million fresh IVF cycles, >65% used ICSI even though <36% involved male factor infertility. ICSI use increased in couples with male factor infertility from 76% in 1996 to 93% in 2012, but it increased by even more i…

Reviewing Author

Robert W. Rebar, MD

Disclosures

Consultant/Advisory BoardMyovant Sciences, Inc.

Editorial BoardsEndoText; Clinical OB/GYN Alert

Leadership Positions in Professional SocietiesAmerican Society for Reproductive Medicine (Member, Ethics Committee)

Robert W. Rebar, MD

Disclosures

Consultant/Advisory BoardMyovant Sciences, Inc.

Editorial BoardsEndoText; Clinical OB/GYN Alert

Leadership Positions in Professional SocietiesAmerican Society for Reproductive Medicine (Member, Ethics Committee)

Is Widespread Use of Intracytoplasmic Sperm Injection in IVF Warranted?

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Reviewing Author