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Prolonged exposure (PE) and eye movement desensitization and reprocessing (EMDR) are commonly used for post-traumatic stress disorder (PTSD). To determine whether these work as well in patients with psychotic disorders, Dutch investigators conducted an 8-week comparison of these treatments in 155 adults with PTSD and schizophrenia (n=95), schizoaffective disorder (n=45), psychotic mood disorders (n=10), or other psychoses (n=5).
Participants continued treatment as usual for the psychotic disorder and were randomized to PE, EMDR, or waiting-list control. Assessments with a PTSD rating scale, but not treatments, were blinded.
At 8 weeks, both active treatments were significantly more effective than the waiting list in reducing PTSD ratings, wit…