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Investigators prospectively evaluated the accuracy of a serial ultrasound clinical pathway for diagnosing appendicitis in children 4 to 17 years of age presenting to a pediatric emergency department (ED) with suspected appendicitis. Per the pathway, if the initial ultrasound result was positive, the patient had a surgical consult; if negative, the patient was discharged; if equivocal or the appendix was not visualized, the patient had repeat clinical reassessments and surgical consultation. Patients with persistent concern for appendicitis underwent interval ultrasounds, and those with equivocal results underwent abdominal computed tomography (CT). The pathway was considered inaccurate if a patient did not have appendicitis at surgery, retu…