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Chronic pelvic pain associated with endometriosis is hard to evaluate and even harder to manage. Investigators sought to demonstrate evidence of sensitization to pain, myofascial dysfunction, and effects on quality of life in a cross-sectional prospective study of women aged 18 to 50 with pain suggestive of endometriosis (18 with current, biopsy-proven endometriosis and 11 with pain only) and 20 pain-free volunteers without evidence of endometriosis.
Sensitization to pain as documented by allodynia (pain in response to normally benign stimuli) and hyperalgesia (increased sensitivity to pain) was present in more women with chronic pelvic pain (with endometriosis [83%] or without [82%]) than in women without histories of pain (15%). Almost all…