What Influences Onset and Persistence of Post–Lumbar Puncture Headache?

Factors that acutely lower cerebrospinal fluid pressure may produce early post–lumbar puncture headache, but other factors affect headache persistence.

Diagnostic lumbar punctures aid in the diagnosis of infections and diseases of the central nervous system. Life-threatening events from lumbar punctures are rare, but post–lumbar (dural) puncture headaches (PDPH) occur in 1% to 36% of patients, depending on the needle type and factors that may lower cerebrospinal fluid (CSF) pressure. To assess factors associated with common adverse events following a lumbar puncture — immediate postprocedural headache, PDPH at 24-hour follow-up, and PDPH receiving a therapeutic blood patch — researchers retrospectively assessed lumbar punctures performed in 338 patients from the Dominantly Inherited Alzheimer Network.

The incidence of adverse events included 73 immediate postprocedural headaches (21.6%), 59…

Reviewing Author

Jaime Toro, MD

Disclosures

Editorial BoardsMultiple Sclerosis and Related Disorders

Jaime Toro, MD

Disclosures

Editorial BoardsMultiple Sclerosis and Related Disorders

What Influences Onset and Persistence of Post–Lumbar Puncture Headache?

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Reviewing Author