What to Do with Asymptomatic Neoplastic Pancreatic Cysts

A new practice guideline recommends that far fewer patients undergo endoscopic ultrasonography, surveillance, and pancreatic resection.

Sponsoring Organization: American Gastroenterological Association

Target Audience: Primary care providers and gastroenterologists

Background and Objective

A comprehensive literature review and formal utilization of the Grades of Recommendation Assessment, Development and Evaluation system were utilized to develop guidelines for the management of asymptomatic neoplastic pancreatic cysts.

What's Changed

In contrast with previous guidelines, recommendations emphasize the existing evidence (such as it is), rather than expert opinion, and recommend less use of endoscopic ultrasonography with fine-needle aspiration (EUS-FNA), less frequent surveillance of patients with pancreatic cysts, and a much higher bar for considering surgical resection.

Key Reco…

Reviewing Author

Chris E. Forsmark, MD

Disclosures

Editorial boardsAmerican Journal of Gastroenterology; Gut; Pancreas