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Interest is growing in endoscopic approaches to promoting weight loss. New intragastric balloons have been developed since the first balloon was withdrawn almost 3 decades ago. In a systematic review of one newer balloon, the Orbera balloon, investigators summarized the results of 7 studies reporting weight loss at 3 and 6 months and 11 studies reporting sustained weight loss after balloon removal.
Results showed the following:
The average weight loss was 12.9 kg after 3 months and 16 kg after 6 months.
Eighty percent of the 6-month weight loss was achieved in the first 3 months.
An average of 52% of weight loss was sustained 1 year after balloon removal.
Two cases of intestinal obstruction occurred.
Balloon leakage was the most common adverse ev…